Developing new medications to treat alcohol use disorder

Medication Development for the Treatment of Alcohol Use Disorder

['FUNDING_U01'] · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · NIH-10917129

This study is looking at new medications that could help people with alcohol use disorder by testing modified versions of existing drugs to see if they can reduce drinking, with the goal of finding better treatments for those who want to manage their alcohol dependence.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorTEXAS TECH UNIVERSITY HEALTH SCIS CENTER (nih funded)
Locations1 site (LUBBOCK, UNITED STATES)
Trial IDNIH-10917129 on ClinicalTrials.gov

What this research studies

This research focuses on creating new medications specifically designed to help individuals struggling with alcohol use disorder (AUD). The team is investigating modified versions of tetracyclines, which have shown promise in reducing alcohol consumption in animal models. By testing these new compounds, the researchers aim to find effective treatments that can help patients manage their alcohol dependence more successfully. The study involves preclinical testing to ensure the safety and efficacy of these new medications before they can be considered for human trials.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with alcohol use disorder who are seeking new treatment options.

Not a fit: Patients who do not have alcohol use disorder or those who are not seeking treatment for their alcohol consumption may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective medications for treating alcohol use disorder, improving outcomes for many patients.

How similar studies have performed: Previous research has shown promise in developing new medications for alcohol use disorder, but this specific approach using chemically modified minocycline is relatively novel.

Where this research is happening

LUBBOCK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.