Developing new materials to help regenerate lost muscle tissue
Official title: Acellular composite hydrogel scaffolds for volumetric muscle regeneration
Funded at New Jersey Institute of Technology · NIH-10555267 · Data updated 2026-11-12
This study is testing new biodegradable materials that help heal and rebuild muscle tissue lost from injuries or treatments, aiming to make recovery easier and more effective for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New Jersey Institute of Technology NIH-funded |
| Lab location | 1 site (Newark, United States) |
| Project start | February 1, 2022 |
| Project end | January 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $199,229 |
| NIH project number | 5R21AR079708-02 |
| Project ID | NIH-10555267 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced volumetric muscle loss due to trauma, surgery, or other medical conditions.
✕Less likely to help
Patients with minor muscle injuries or those who do not have significant muscle loss may not benefit from this research.
What this research studies
This research focuses on creating innovative biodegradable scaffolds designed to enhance the repair of skeletal muscle tissue lost due to traumatic injuries, cancer treatments, or cosmetic procedures. The approach aims to actively stimulate the growth of blood vessels and muscle cells, which are crucial for effective muscle regeneration. By implanting these scaffolds into areas of volumetric muscle loss, the research seeks to improve the body's natural healing processes and functional outcomes. Patients may benefit from advancements in reconstructive procedures that utilize these new materials for better recovery.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery and functional outcomes for patients suffering from significant muscle loss.
How similar studies have gone: Previous research has shown promise in using biomaterials for tissue regeneration, indicating potential success for this novel approach.
Where this research is happening
-
New Jersey Institute of Technology
Newark, United States Active
Researchers
- Principal investigator: Grasman, Jonathan M. — New Jersey Institute of Technology
- Study coordinator: Grasman, Jonathan M.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.