Developing new imaging techniques for studying brain cells and tissues
Official title: Novel Nano- and Immuno-Probes for Multicolor Electron Microscopy of Neural Cells and Tissues
Funded at Harvard University · NIH-11048017 · Data updated 2026-11-12
This study is working on new ways to take better pictures of brain cells and tissues to help us understand how they work in both healthy and sick conditions, using special tools that make the imaging clearer and more effective.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard University NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | December 11, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $621,500 |
| NIH project number | 1R01NS134846-01A1 |
| Project ID | NIH-11048017 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with neurological conditions or diseases that affect brain function.
✕Less likely to help
Patients with conditions unrelated to neural cell function or those who do not have access to advanced imaging technologies may not benefit from this research.
What this research studies
This research aims to create advanced methods for imaging neural cells and tissues by combining molecular and ultrastructural imaging techniques. It focuses on understanding how the structure and molecular characteristics of neural networks interact in both healthy and diseased states. The approach involves developing smaller antibody fragments and innovative nanoparticle probes to improve the delivery and effectiveness of imaging. By overcoming current limitations in imaging methods, this research seeks to provide clearer insights into neural physiology.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for neurological diseases by enhancing our understanding of brain cell function.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for studying neural cells, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
-
Harvard University
Cambridge, United States Active
Researchers
- Principal investigator: Prigozhin, Maxim — Harvard University
- Study coordinator: Prigozhin, Maxim
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.