Developing new imaging probes for better physiological chemistry sensing
New Classes of Electron Paramagnetic Resonance Imaging Probes With High-Spin Metal Complexes
This study is working on new metal-based tools that can help doctors take safer and clearer images of the body, combining advanced techniques to better understand how our bodies work without using harmful methods.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10911225 on NIH RePORTER |
What this research studies
This research focuses on creating innovative metal complexes that can be used as noninvasive probes for electron paramagnetic resonance imaging (EPRI). By overcoming the limitations of current imaging techniques, the goal is to integrate EPRI with conventional MRI to produce detailed chemical and anatomical maps of the body. The study will explore high-spin metal complexes that allow for safer imaging without the need for dangerous high-energy microwaves. This approach aims to enhance the capabilities of EPRI, making it a more effective tool for understanding physiological chemistry.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring detailed imaging of physiological chemistry, such as those with complex medical conditions that are difficult to diagnose.
Not a fit: Patients who do not require advanced imaging techniques or those with conditions that can be adequately diagnosed with existing methods may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to advanced imaging techniques that provide more accurate and comprehensive insights into physiological conditions.
How similar studies have performed: While the integration of EPRI with MRI is a novel approach, previous research has shown promise in using metal complexes for imaging, suggesting potential for success in this area.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Zadrozny, Joseph M — Ohio State University
- Study coordinator: Zadrozny, Joseph M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.