Developing new HIV vaccines using advanced immunogens and antibodies
Official title: Immunogen and Antibody Core
Funded at University of California at Davis · NIH-11062308 · Data updated 2026-11-12
This study is working on new HIV vaccines that use special proteins to help your immune system make stronger antibodies, with the goal of providing better protection against the virus.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | December 17, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $464,657 |
| NIH project number | 1P01AI181044-01A1 |
| Project ID | NIH-11062308 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for HIV or those living with HIV who may benefit from improved vaccine strategies.
✕Less likely to help
Patients who are not at risk for HIV or those who have already developed effective immunity against the virus may not receive benefit from this research.
What this research studies
This research focuses on creating innovative vaccines for HIV by using specially designed proteins that can stimulate the immune system to produce broadly neutralizing antibodies. The approach involves synthesizing and purifying advanced HIV envelope proteins that can enhance the immune response, particularly by recruiting T cells to help in antibody development. By testing these immunogens in various models, the research aims to improve the effectiveness of HIV vaccines and provide better protection against the virus.
Why it matters
Potential benefit: If successful, this research could lead to more effective HIV vaccines that provide broader protection against various strains of the virus.
How similar studies have gone: Previous research has shown promise in using similar immunogen strategies to enhance immune responses, indicating potential for success in this novel approach.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Moore, Penny — University of California at Davis
- Study coordinator: Moore, Penny
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.