Developing new dye molecules for better imaging and treatment of brain cancer
Ionic Liquid-Coated NIR-II Polymer Conjugates as Targeted Brain Theranostics
This study is testing new dyes that can help doctors see hard-to-treat brain tumors more clearly using special imaging, which could lead to better ways to diagnose and treat these cancers.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10908535 on NIH RePORTER |
What this research studies
This research focuses on creating innovative dye molecules that emit light in the near-infrared II (NIR-II) region, which can improve the imaging of diffuse brain tumors that are difficult to treat. By using these dyes, the research aims to enhance the resolution of images taken of brain cancers, allowing for better visualization and potentially more effective treatment options. The dyes will be encapsulated in specialized nanocarriers to ensure they can effectively penetrate the blood-brain barrier and reach the tumor site. This approach could lead to significant advancements in both the diagnosis and treatment of non-operable brain cancers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with non-operable brain cancers who are 21 years or older.
Not a fit: Patients with operable brain tumors or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with improved imaging techniques and more effective treatment options for non-operable brain cancers.
How similar studies have performed: Other research has shown promise in using near-infrared imaging techniques for cancer treatment, but this specific approach with NIR-II dyes is relatively novel.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Watkins, Davita L. — Ohio State University
- Study coordinator: Watkins, Davita L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.