Developing new drugs to treat tuberculosis more effectively
Official title: Harnessing Amide Linkers for Antitubercular Drug Development
Funded at Rutgers Biomedical and Health Sciences · NIH-11013311 · Data updated 2026-11-12
This study is working on new medicines to help fight tuberculosis (TB) by making treatments shorter and more effective, especially for those who have drug-resistant TB.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project start | February 1, 2024 |
| Project end | January 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $52,420 |
| NIH project number | 5F30AI176796-02 |
| Project ID | NIH-11013311 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with tuberculosis, particularly those with drug-resistant strains.
✕Less likely to help
Patients with non-infectious diseases or those who do not have tuberculosis will not benefit from this research.
What this research studies
This research focuses on creating innovative drugs to combat tuberculosis (TB), a major global health issue. It aims to develop new antitubercular agents that can reduce the duration of treatment and overcome drug resistance. The approach involves understanding how certain drugs are activated within the bacteria and designing prodrugs that can effectively penetrate the TB bacteria's protective envelope. By targeting the metabolism of the bacteria, the research seeks to enhance the efficacy of TB treatments.
Why it matters
Potential benefit: If successful, this research could lead to more effective and shorter treatment options for tuberculosis patients.
How similar studies have gone: Previous research has shown promise in developing prodrugs for other bacterial infections, indicating potential success for this novel approach in tuberculosis treatment.
Where this research is happening
-
Rutgers Biomedical and Health Sciences
Newark, United States Active
Researchers
- Principal investigator: Kodali, Swetha — Rutgers Biomedical and Health Sciences
- Study coordinator: Kodali, Swetha
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.