Developing new drugs to treat obesity by targeting specific enzymes.
Discovery and optimization of novel, selective HDAC11 inhibitors for the treatment of obesity and related diseases.
This study is looking at new ways to help people with obesity by targeting a specific enzyme called HDAC11, which affects how our body uses fat, with the hope of improving metabolism and overall health.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Myracle Therapeutics INC NIH-funded |
| Lab location | 1 site (East Hanover, United States) |
| Project ID | NIH-10921027 on NIH RePORTER |
What this research studies
This research focuses on creating selective inhibitors for the enzyme HDAC11, which may help improve metabolic health and treat obesity. By understanding how HDAC11 affects fat tissue, the researchers aim to enhance energy expenditure and reduce fat dysfunction. The approach involves studying the effects of these inhibitors on brown and white adipose tissues, which play crucial roles in metabolism. Patients may benefit from new therapeutic options that target the underlying mechanisms of obesity and related metabolic diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals struggling with obesity or related metabolic disorders.
Not a fit: Patients who are not affected by obesity or metabolic diseases may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for obesity and improve metabolic health in patients.
How similar studies have performed: Other research has shown promise in targeting metabolic pathways for obesity treatment, indicating potential success for this approach.
Where this research is happening
East Hanover, United States
- Myracle Therapeutics INC — East Hanover, United States (Active)
Researchers
- Principal investigator: Bell, Dawn — Myracle Therapeutics INC
- Study coordinator: Bell, Dawn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.