Developing new drugs to treat and prevent malaria.

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['FUNDING_OTHER'] · PORTLAND VA MEDICAL CENTER · NIH-11052837

This study is working on developing new oral medications to treat and prevent malaria, aiming to create effective options for people battling this serious disease, especially in light of growing drug resistance.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPORTLAND VA MEDICAL CENTER (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-11052837 on ClinicalTrials.gov

What this research studies

This research focuses on creating and optimizing new antiparasitic drugs specifically aimed at treating and preventing malaria, a serious tropical disease. The laboratory employs advanced drug design and chemical synthesis techniques to develop five novel classes of antimalarial compounds that have shown effectiveness in laboratory models. These compounds are designed to be taken orally and have the potential to be curative, addressing the challenge of drug resistance in malaria treatment. The research aims to translate these findings into viable treatments for patients suffering from malaria.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at risk of malaria infection, particularly those living in or traveling to endemic regions.

Not a fit: Patients who do not live in malaria-endemic areas or who are not at risk of malaria infection may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of more effective and accessible treatments for malaria, potentially saving lives.

How similar studies have performed: Previous research has shown success in developing new antimalarial drugs using similar innovative approaches, indicating a promising avenue for future breakthroughs.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.