Developing new drugs to manage pain and substance use disorders

SPIGELMAN (UCLA) - MCSP- EXPLORATORY CHEMISTRY (EC)

NIH-funded research Albany Molecular Research, INC. · NIH-11189220

This study is working on new medications to help people manage pain better and tackle issues with substance use, aiming to create treatments that could improve your quality of life.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAlbany Molecular Research, INC. NIH-funded
Lab location1 site (Albany, United States)
Project IDNIH-11189220 on NIH RePORTER

What this research studies

This research focuses on creating new medications aimed at improving pain management and addressing substance use disorders. It utilizes advanced medicinal chemistry techniques, including the design and synthesis of small molecules that can selectively inhibit specific enzymes related to these conditions. The project involves a thorough evaluation of these compounds through various assays to determine their effectiveness and safety. Patients may benefit from innovative treatments that could enhance their quality of life and pain management options.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from chronic pain conditions or substance use disorders.

Not a fit: Patients who do not have chronic pain or substance use issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new, effective treatments for managing pain and reducing substance use disorders.

How similar studies have performed: Previous research in medicinal chemistry has shown promise in developing effective treatments for pain and addiction, indicating a potential for success in this approach.

Where this research is happening

Albany, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.