Developing new drugs to fight antibiotic-resistant bacteria.
Official title: Chemistry Center for Combatting Antibiotic-Resistant Bacteria (CC4CARB)
Funded at Research Triangle Institute · NIH-11270624 · Data updated 2026-11-12
This study is all about making new chemical compounds to help scientists find better antibiotics for tough-to-treat infections caused by resistant bacteria, which could lead to new treatment options for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $3,606,416 |
| NIH project number | 75N93021C00002-P00014-9999-1 |
| Project ID | NIH-11270624 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from infections caused by Gram-negative bacteria that are resistant to current antibiotic treatments.
✕Less likely to help
Patients with infections caused by bacteria that are not Gram-negative or those who do not have antibiotic-resistant infections may not benefit from this research.
What this research studies
This research focuses on creating and providing a collection of specially designed chemical compounds aimed at discovering new antibacterial drugs. The primary goal is to target Gram-negative bacteria, which are known for their resistance to existing antibiotics. By synthesizing these compounds, the research aims to support scientists in their efforts to develop effective treatments against infections caused by these resistant bacteria. Patients may benefit from new therapeutic options that could emerge from this innovative drug discovery process.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively treat infections caused by antibiotic-resistant bacteria.
How similar studies have gone: Other research efforts targeting antibiotic resistance have shown promise in developing new treatments, indicating that this approach could be effective.
Where this research is happening
-
Research Triangle Institute
Research Triangle Park, United States Active
Researchers
- Principal investigator: Blough, Bruce — Research Triangle Institute
- Study coordinator: Blough, Bruce
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.