Developing new drugs to fight antibiotic-resistant bacteria.

CHEMISTRY CENTER FOR COMBATING ANTIBIOTIC-RESISTANT BACTERIA (CC4CARB)

['FUNDING_OTHER'] · RESEARCH TRIANGLE INSTITUTE · NIH-10788038

This study is working on creating new chemical compounds to help scientists find better antibiotics for tough infections caused by Gram-negative bacteria, which could lead to more effective treatments for patients dealing with antibiotic-resistant infections.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRESEARCH TRIANGLE INSTITUTE (nih funded)
Locations1 site (RESEARCH TRIANGLE PARK, UNITED STATES)
Trial IDNIH-10788038 on ClinicalTrials.gov

What this research studies

The Chemistry Center for Combating Antibiotic-Resistant Bacteria (CC4CARB) focuses on creating and providing a variety of specially designed chemical compounds to help scientists discover new antibacterial medications. This initiative specifically targets Gram-negative bacteria, which are known for their resistance to many existing antibiotics. By synthesizing these compound libraries, the research aims to support the scientific community in finding effective treatments against these challenging infections. Patients may benefit from the eventual development of new antibiotics that can effectively treat resistant bacterial infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from infections caused by Gram-negative bacteria that are resistant to current antibiotic treatments.

Not a fit: Patients with infections caused by non-Gram-negative bacteria or those who do not have antibiotic-resistant infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively treat infections caused by antibiotic-resistant bacteria.

How similar studies have performed: Other research initiatives targeting antibiotic resistance have shown promise in developing new treatments, indicating that this approach has potential for success.

Where this research is happening

RESEARCH TRIANGLE PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.