Developing new drugs to fight antibiotic-resistant bacteria.
CHEMISTRY CENTER FOR COMBATING ANTIBIOTIC-RESISTANT BACTERIA (CC4CARB)
This study is working on making new chemical compounds to help scientists find better antibiotics for tough infections caused by Gram-negative bacteria, which are often hard to treat, so that patients can have more effective options for their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-10553584 on NIH RePORTER |
What this research studies
This research focuses on creating and providing a variety of specially designed chemical compounds aimed at discovering new antibacterial drugs. The goal is to specifically target Gram-negative bacteria, which are known for their resistance to many existing antibiotics. By synthesizing these compounds, the research aims to support scientists in their efforts to find effective treatments against these challenging infections. Patients may benefit from the eventual development of new antibiotics that can effectively treat resistant bacterial infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from infections caused by Gram-negative bacteria, particularly those that are resistant to current antibiotic treatments.
Not a fit: Patients with infections caused by non-Gram-negative bacteria or those who do not have antibiotic-resistant infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively treat infections caused by antibiotic-resistant bacteria.
How similar studies have performed: Other research efforts targeting antibiotic resistance have shown promise in developing new treatments, indicating that this approach has potential for success.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Blough, Bruce — Research Triangle Institute
- Study coordinator: Blough, Bruce
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.