Developing new drugs for Sickle Cell Anemia
Small Molecule Therapeutics for Sickle Cell Anemia
['FUNDING_OTHER'] · EMORY UNIVERSITY · NIH-11036330
This study is looking for new medicines to help people with Sickle Cell Disease by using a special imaging technique to find ways to stop red blood cells from sickling, which can lead to better health for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11036330 on ClinicalTrials.gov |
What this research studies
This research focuses on finding new small molecule therapeutics to treat Sickle Cell Disease (SCD), a genetic condition that causes severe complications due to the sickling of red blood cells. The approach involves using an innovative imaging assay that can detect the sickled shape of red blood cells and identify potential anti-sickling agents through high throughput screening. By targeting the pathways that affect hemoglobin polymerization, the research aims to develop effective treatments that could improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Sickle Cell Disease, particularly those of African heritage.
Not a fit: Patients with other forms of anemia or those who do not have Sickle Cell Disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective and accessible treatments for patients with Sickle Cell Disease.
How similar studies have performed: Previous research has shown promise in developing anti-sickling agents, but this approach utilizing high throughput screening is relatively novel.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ARCHER, DAVID R — EMORY UNIVERSITY
- Study coordinator: ARCHER, DAVID R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.