Developing new conduits to repair large nerve injuries
Official title: Hierarchically-Structured Conduits with Programmed Release of Neurotrophic Factors for Repairing Large Defects in Thick Nerves
Funded at Georgia Institute of Technology · NIH-11085068 · Data updated 2026-11-12
This study is testing new, friendly materials to create special tubes that help heal serious nerve injuries, aiming to make recovery easier and faster for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | May 15, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $440,388 |
| NIH project number | 5R01NS126183-03 |
| Project ID | NIH-11085068 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with significant peripheral nerve injuries requiring surgical intervention.
✕Less likely to help
Patients with minor nerve injuries or those who do not require surgical repair may not benefit from this research.
What this research studies
This research focuses on creating innovative nerve guidance conduits (NGCs) designed to repair significant injuries in thick peripheral nerves. The approach involves using advanced materials and techniques, including biocompatible and biodegradable polymers, to fabricate multi-tubular conduits that guide nerve regeneration. By mimicking the natural structure of nerves and enhancing the biochemical environment, the conduits aim to restore nerve function and continuity. Patients may benefit from improved surgical outcomes and recovery times through this novel technology.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with large nerve injuries, potentially improving recovery and quality of life.
How similar studies have gone: Previous research has shown promise in using bioengineered conduits for nerve repair, indicating potential success for this novel approach.
Where this research is happening
-
Georgia Institute of Technology
Atlanta, United States Active
Researchers
- Principal investigator: Xia, Younan — Georgia Institute of Technology
- Study coordinator: Xia, Younan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.