Developing new chemical methods for creating complex molecules
Stereoselective Nickel-Catalyzed Coupling and Cascade Reactions
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10849672
This study is exploring new ways to help create complex molecules using a special chemical process, which could lead to better and more effective medicines for people.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10849672 on ClinicalTrials.gov |
What this research studies
This research focuses on creating innovative chemical methods for cross-coupling reactions, which are essential for forming complex and strained molecular structures. By utilizing nickel as a catalyst, the project aims to enhance the efficiency of reactions involving typically unreactive functional groups, such as alkyl alcohol derivatives. The goal is to develop stereoselective reactions that can lead to the production of new pharmaceutical agents, potentially improving drug development processes.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with conditions that could be treated by new drugs developed through these innovative chemical methods.
Not a fit: Patients who are not seeking new treatment options or those with conditions unrelated to the pharmaceutical agents developed from this research may not benefit.
Why it matters
Potential benefit: If successful, this research could lead to the creation of new and more effective pharmaceutical agents.
How similar studies have performed: Other research in the field of stereoselective reactions has shown promise, indicating that this approach could lead to significant advancements in drug development.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JARVO, ELIZABETH REINHARDT — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: JARVO, ELIZABETH REINHARDT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.