Developing new cancer-fighting peptides from moroidin
Official title: Biosynthetic Development and Diversification of Moroidin Peptides for Cancer Applications
Funded at University of Michigan at Ann Arbor · NIH-10994826 · Data updated 2026-11-12
This study is working on developing new versions of moroidin peptides that could help treat cancer better, using special techniques to make more of these helpful substances from plants, which could lead to improved treatments for patients like you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 1F31GM155959-01 |
| Project ID | NIH-10994826 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with cancer who are seeking new treatment options.
✕Less likely to help
Patients who are not currently undergoing cancer treatment or those with non-cancerous conditions may not benefit from this research.
What this research studies
This research focuses on creating and improving moroidin peptides, which are promising candidates for cancer treatment. By using advanced biosynthetic techniques, the team aims to produce a variety of moroidin analogs that could enhance their effectiveness against cancer cells. The approach involves engineering specific plant systems to maximize the production of these peptides, allowing for better availability and potential therapeutic applications. Patients may benefit from new, more effective cancer treatments derived from these innovative peptides.
Why it matters
Potential benefit: If successful, this research could lead to the development of new and more effective cancer therapies.
How similar studies have gone: Other research has shown promise in developing peptide-based therapies for cancer, indicating that this approach could be effective.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Shafiq, Khadija — University of Michigan at Ann Arbor
- Study coordinator: Shafiq, Khadija
Related research
Other NIH-funded projects on the same topics.
-
Expanding genetic testing for cancer risk in patients and families
This study is working to make it easier for cancer patients in Michigan to get genetic testing for cancer risk by improving how doctors gather family history and assess genetic risks, so that more people can receive the important evaluations they need.
-
HEARTS hypertension and diabetes care in Guatemala
This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.
-
Why the retina can sometimes heal itself and how we might help it heal
This NIH grant explores how inflammation and neural cells interact in the zebrafish retina to understand retinal neuron death and regeneration, with potential implications for human vision.
-
Integrated Heart Health: A HEARTS-based approach to hypertension and diabetes in Guatemala
A study tests a team-based, stepwise care model to improve blood pressure and blood sugar control for people with both hypertension and diabetes in Guatemala.
-
Understanding how work exposures and genes influence ALS risk
A study is building a long-term group of people at higher risk for ALS to see how their jobs, exposures at work, and genes together affect if and when the disease might develop.
-
An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya
A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.