Developing new brain imaging technology for children and adults with autism
Official title: Flexible, scalable, and generalizable photogrammetric head modeling for high-density diffuse optical tomography
Funded at Esperimage LLC · NIH-11008418 · Data updated 2026-11-12
This study is working on new ways to take pictures of the brain using special wearable technology, making it easier and more comfortable for both kids and adults with autism to get checked, so we can spot changes in brain function earlier and find better ways to help them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Esperimage LLC NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 5, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $446,490 |
| NIH project number | 1R41MH138258-01 |
| Project ID | NIH-11008418 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include children and adults diagnosed with autism spectrum disorder, as well as those at risk for developing ASD.
✕Less likely to help
Patients without autism spectrum disorder or those who do not have any neurodevelopmental concerns may not benefit from this research.
What this research studies
This research focuses on creating advanced brain imaging techniques that are flexible and efficient, specifically designed to overcome the limitations of traditional imaging methods like fMRI. By utilizing wearable optical technology, the project aims to provide naturalistic brain imaging for both children and adults, particularly those with autism spectrum disorder (ASD). The goal is to improve early detection of brain function alterations associated with ASD, which could lead to better treatment strategies and outcomes. The research will involve innovative data registration and modeling procedures to enhance the accuracy of brain imaging.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of autism-related brain function changes, improving treatment options for affected individuals.
How similar studies have gone: Previous research has shown promise in using optical neuroimaging techniques for brain mapping, indicating potential success for this innovative approach.
Where this research is happening
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Esperimage LLC
Saint Louis, United States Active
Researchers
- Principal investigator: Trobaugh, Jason Wayne — Esperimage LLC
- Study coordinator: Trobaugh, Jason Wayne
Related research
Other NIH-funded projects on the same topics.
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Wearable 3D head modeling to improve natural brain scans for kids and adults
This project builds flexible 3‑D head models and data alignment tools so a lightweight wearable optical brain scanner can map natural brain activity in children and adults, including those with autism.
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Wearable technology for brain imaging in children and adults
This study is testing a new wearable device that helps take better pictures of the brain, especially for kids and adults with autism, so we can spot changes in brain function earlier and provide support when it's needed most.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.