Developing new biomarkers to understand circadian timing in health
Real-time breath metabolomics: A new direction for circadian biomarkers
This study is looking to develop a simple blood test that can help figure out your body's natural clock, which could lead to better treatments for health issues like metabolic disorders and cancer by timing medications to match your body's rhythms.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10695164 on NIH RePORTER |
What this research studies
This research aims to create effective diagnostic tools that can determine an individual's biological clock using a single blood sample. By analyzing proteins that fluctuate in rhythm with the body's circadian cycles, the study seeks to improve our understanding of how disruptions in these cycles can lead to various health issues, including metabolic disorders and cancers. The goal is to enable personalized treatment plans that align medication timing with the body's natural rhythms, potentially enhancing treatment efficacy and minimizing side effects.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 who are experiencing health issues related to circadian rhythm disruptions, such as metabolic disorders or cancers.
Not a fit: Patients who are not experiencing any health issues related to circadian rhythms or those under 21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for various health conditions linked to circadian rhythm disruptions.
How similar studies have performed: Previous research has shown promise in using circadian biomarkers for improving treatment outcomes, indicating that this approach could be a significant advancement in personalized medicine.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Czeisler, Charles a — Brigham and Women's Hospital
- Study coordinator: Czeisler, Charles a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.