Developing new biologic drugs using advanced screening techniques

High Content Screening for Bifunctional Chimera Biologics

NIH-funded research Heligenics INC · NIH-11065006

This study is looking for new types of medicines that can boost your immune system to help treat cancer, obesity, and autoimmune diseases, so that patients can have safer and more effective treatment options.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionHeligenics INC NIH-funded
Lab location1 site (Henderson, United States)
Project IDNIH-11065006 on NIH RePORTER

What this research studies

This research focuses on creating and screening new bifunctional biologic drugs that can enhance immune responses and treat conditions like cancer, obesity, and autoimmune diseases. Using a novel high-throughput screening method called the GigaAssay, the team will evaluate vast libraries of protein variants to identify those with improved therapeutic effects. Patients may benefit from more effective and safer treatments derived from these biologics, which are designed to stimulate cellular functions in a targeted manner.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from autoimmune diseases, cancer, obesity, or related conditions who may benefit from advanced biologic treatments.

Not a fit: Patients with conditions not related to immune response or those who do not respond to biologic therapies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of more effective and safer biologic therapies for various diseases.

How similar studies have performed: Previous research has shown success in developing biologic drugs using high-throughput screening methods, indicating a promising approach for this project.

Where this research is happening

Henderson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancer therapy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.