Developing new antiviral agents using specialized peptides
Genetically encoded bicyclic peptide libraries for the discoveryof novel antiviral agents
This study is exploring new types of molecules that can better target and fight viruses, like the coronavirus, which could lead to improved treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11243888 on NIH RePORTER |
What this research studies
This research focuses on creating bicyclic peptides, which are unique molecules with two interconnected rings that can bind more effectively to viral proteins. By using a technique called phage display, researchers aim to discover these peptides from large libraries, enhancing their ability to target and neutralize viruses like the novel coronavirus. The study involves innovative methods to incorporate specific amino acids into these peptides, potentially leading to more effective antiviral therapies. Patients may benefit from new treatments that are developed through this advanced peptide technology.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by viral infections, particularly those caused by coronaviruses.
Not a fit: Patients with viral infections not related to coronaviruses may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel antiviral medications that are more effective against viruses.
How similar studies have performed: Previous research has shown promise in using similar peptide-based approaches for antiviral drug development, indicating potential for success in this area.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Tharp, Jeffery Micheal — Indiana University Indianapolis
- Study coordinator: Tharp, Jeffery Micheal
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.