Developing new antifungal treatments for invasive fungal infections
Official title: BLRD Research Career Scientist Award Application
Funded at Northport VA Medical Center · NIH-10948088 · Data updated 2026-11-12
This study is working on new antifungal medicines to help people, especially veterans, who are at risk for serious fungal infections, aiming to find better treatments that work well and don’t lead to resistance.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northport VA Medical Center NIH-funded |
| Lab location | 1 site (Northport, United States) |
| Project start | October 1, 2020 |
| Project end | September 30, 2025 |
| Funding year | 2025 |
| NIH project number | 5IK6BX005386-05 |
| Project ID | NIH-10948088 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients with compromised immune systems, such as those undergoing chemotherapy, organ transplant recipients, or individuals with advanced HIV/AIDS.
✕Less likely to help
Patients with non-invasive fungal infections or those who are not immunocompromised may not receive benefit from this research.
What this research studies
This research focuses on creating new antifungal medications to combat invasive fungal infections, particularly in vulnerable populations such as veterans. Led by an experienced physician-scientist, the project combines clinical insights with laboratory research to address the limitations of current antifungal therapies, which often have narrow effectiveness and can lead to resistance. The research involves collaboration with a start-up company dedicated to antifungal drug development, aiming to bring innovative treatments to the clinic. By studying lipid-mediated infectious diseases, the research seeks to enhance our understanding of fungal infections and improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer antifungal treatments for patients suffering from invasive fungal infections.
How similar studies have gone: Previous research has shown promise in developing new antifungal agents, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
-
Northport VA Medical Center
Northport, United States Active
Researchers
- Principal investigator: Del Poeta, Maurizio — Northport VA Medical Center
- Study coordinator: Del Poeta, Maurizio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.