Developing new antibodies to prevent HIV infection

Next Generation Development of Broadly Neutralizing HIV Antibodies for Prevention

NIH-funded research Advanced Bioscience Laboratories, INC. · NIH-11041822

This study is looking at new types of antibodies that can help fight HIV, with the goal of making treatments and prevention methods better for people living with or at risk of HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAdvanced Bioscience Laboratories, INC. NIH-funded
Lab location1 site (Kensington, United States)
Project IDNIH-11041822 on NIH RePORTER

What this research studies

This research focuses on creating broadly neutralizing antibodies (bnAbs) that can effectively target and neutralize the HIV virus. By evaluating multiple bnAbs that recognize different parts of the HIV envelope, the research aims to improve treatment and prevention strategies for HIV. The approach includes testing antibodies like VRC01, PGDM1400, and PGT121, and exploring modifications to enhance their effectiveness and longevity in the body. Patients may benefit from these advancements in HIV prevention and treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at high risk of HIV infection or those currently living with HIV who may benefit from enhanced treatment options.

Not a fit: Patients who are not at risk for HIV or those who are already receiving effective treatment may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective HIV prevention methods and improved treatment options for patients living with HIV.

How similar studies have performed: Previous research has shown promise in using broadly neutralizing antibodies for HIV treatment and prevention, indicating a potential for success in this novel approach.

Where this research is happening

Kensington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.