Developing new antibiotics to fight Salmonella infections
BLRD Research Career Scientist Award Application
This study is looking into how Salmonella bacteria become resistant to antibiotics so that researchers can create new treatments to help people who are sick with Salmonella infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Eastern Colorado Health Care System NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10948076 on NIH RePORTER |
What this research studies
This research focuses on understanding how Salmonella bacteria become resistant to antibiotics and aims to develop new antibiotics to combat these infections. The team will investigate specific proteins and molecules that regulate the bacteria's ability to survive and cause disease. By studying the mechanisms of bacterial virulence and antibiotic resistance, the researchers hope to create effective treatments for patients suffering from Salmonella infections. This work is crucial given the rising rates of multidrug-resistant Salmonella worldwide.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with Salmonella infections, particularly those with antibiotic-resistant strains.
Not a fit: Patients with infections caused by non-Salmonella pathogens or those who do not have antibiotic-resistant infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel antibiotics that effectively treat multidrug-resistant Salmonella infections, potentially saving lives.
How similar studies have performed: Previous research has shown promise in developing antibiotics targeting bacterial transcription mechanisms, indicating potential success for this approach.
Where this research is happening
Aurora, UNITED STATES
- VA Eastern Colorado Health Care System — Aurora, United States (Active)
Researchers
- Principal investigator: Vazquez-Torres, Andres — VA Eastern Colorado Health Care System
- Study coordinator: Vazquez-Torres, Andres
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.