Developing MRI markers to assess treatment response in Crohn's disease
Robust quantitative MR imaging markers of response to therapy in Crohn’s Disease
This study is looking at new ways to use MRI scans to better understand and track how Crohn's disease is affecting young people, so doctors can personalize treatments and help them feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11054575 on NIH RePORTER |
What this research studies
This research focuses on Crohn's disease, a chronic inflammatory condition affecting the gastrointestinal tract, which often leads to significant health challenges, especially in young individuals. The project aims to create non-invasive MRI imaging techniques that can accurately measure disease activity and monitor how well patients respond to treatments. By utilizing advanced imaging protocols, the researchers hope to provide objective markers that can help tailor therapy to individual patients, improving their overall management and outcomes. This approach represents a shift towards more proactive treatment strategies in Crohn's disease care.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Crohn's disease, particularly those experiencing active symptoms or undergoing treatment.
Not a fit: Patients with Crohn's disease who are in complete remission or those who do not have access to MRI facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and management of Crohn's disease, ultimately improving patient outcomes and quality of life.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for monitoring Crohn's disease, but this specific approach is innovative and aims to enhance existing methods.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Kurugol, Sila — Boston Children's Hospital
- Study coordinator: Kurugol, Sila
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.