Developing mouse models and drug testing for polycystic kidney disease
Biomedical Research Core 2 - Rodent Models & Drug Testing Core
This study is working on new mouse models to help us learn more about polycystic kidney disease (PKD) and find better treatments, so that patients like you can have more options for managing the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kansas Medical Center NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project ID | NIH-10884897 on NIH RePORTER |
What this research studies
This research focuses on creating innovative mouse models to better understand polycystic kidney disease (PKD) and to evaluate potential drug therapies. By exploring specific gene networks and providing essential drug-testing services, the project aims to overcome existing barriers in PKD research. Patients may benefit from the development of new therapeutic targets and biomarkers that could lead to improved treatment options. The research also includes maintaining a repository of PKD rodent models for further studies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autosomal dominant polycystic kidney disease (ADPKD).
Not a fit: Patients with other forms of kidney disease or those not diagnosed with ADPKD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments and improved understanding of polycystic kidney disease for patients.
How similar studies have performed: Previous research has shown success in developing animal models for kidney diseases, indicating that this approach has potential for meaningful advancements.
Where this research is happening
Kansas City, United States
- University of Kansas Medical Center — Kansas City, United States (Active)
Researchers
- Principal investigator: Tran, Pamela Vivian — University of Kansas Medical Center
- Study coordinator: Tran, Pamela Vivian
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.