Developing models to study childhood cystic kidney disease
UAB Childhood Cystic Kidney Disease Core Center (UAB-CCKDCC) - In Vivo Bioassay and Model Development Resource
['FUNDING_OTHER'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10884928
This study is working on new ways to understand childhood cystic kidney disease by using special animal models and tools, with the hope that it will help find better treatments to slow down cyst growth for kids with this condition.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-10884928 on ClinicalTrials.gov |
What this research studies
This research focuses on creating and distributing animal models and biosensors to better understand childhood cystic kidney disease (CCKD). By collaborating with the PKD Consortium, the team aims to streamline research processes and improve access to clinical data and biological materials from CCKD patients. The goal is to analyze the mechanisms behind cyst formation and progression, which could lead to more effective treatments. Patients may benefit from the development of new drugs that can slow down cyst growth.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with cystic kidney diseases, particularly those with autosomal dominant or recessive forms.
Not a fit: Patients with non-cystic kidney diseases or those not diagnosed with childhood cystic kidney diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for childhood cystic kidney disease.
How similar studies have performed: Other research has shown success in developing animal models for kidney diseases, indicating that this approach has potential for meaningful advancements.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YODER, BRADLEY K. — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: YODER, BRADLEY K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult Polycystic Kidney Disease, Animal Disease Models