Developing models to study cancer and test new therapies
Preclinical Models and Therapeutics Core
This study is all about making special models from patients' tumors to learn more about cancer and find better treatments, so we can better understand how different therapies might work for you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11015502 on NIH RePORTER |
What this research studies
This research focuses on creating and characterizing patient-derived tumor models, including xenografts and organoids, to better understand cancer biology and evaluate new cancer treatments. By using these models, researchers can study the genetic and biological characteristics of tumors from patients, which helps in predicting how these tumors will respond to various therapies. The project aims to improve the accuracy of preclinical studies by maintaining the essential features of the original tumors, thereby providing a more reliable platform for testing new anti-cancer drugs.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with specific types of cancers, particularly those whose tumors can be used to create patient-derived tumor xenografts or organoids.
Not a fit: Patients with cancers that do not have suitable tumor samples for modeling may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments tailored to individual patients' tumor characteristics.
How similar studies have performed: Previous research has shown success in using patient-derived tumor models to enhance the understanding of cancer biology and improve drug testing outcomes.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Inghirami, Giorgio — New York University School of Medicine
- Study coordinator: Inghirami, Giorgio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.