Developing methods to predict Alzheimer's disease progression using biomarkers
Time-Dynamic Tree-Based Methods for Personalized Alzheimer's Disease Prediction
['FUNDING_R03'] · JOHNS HOPKINS UNIVERSITY · NIH-10890391
This study is looking to find better ways to spot people at risk of developing Alzheimer's Disease by using new methods to analyze their health data, which could help doctors make earlier and more personalized treatment decisions.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10890391 on ClinicalTrials.gov |
What this research studies
This research aims to enhance the understanding of biomarkers related to preclinical Alzheimer's Disease (AD) by utilizing innovative tree-based methods. It focuses on creating algorithms that can identify high-risk individuals for cognitive decline based on their biomarker profiles and other risk factors. By analyzing longitudinal data, the project seeks to provide personalized predictions of disease progression, potentially allowing for earlier interventions. The goal is to improve clinical decision-making and patient outcomes in Alzheimer's care.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with early signs of cognitive decline or relevant biomarker profiles.
Not a fit: Patients with advanced Alzheimer's disease or those without any risk factors for cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate predictions of Alzheimer's disease progression, enabling timely interventions.
How similar studies have performed: Previous research has shown promise in using similar biomarker-based approaches for predicting Alzheimer's disease, indicating potential for success in this novel methodology.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHU, YUXIN — JOHNS HOPKINS UNIVERSITY
- Study coordinator: ZHU, YUXIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease diagnosis