Developing methods to analyze multiple genetic and epigenetic factors in single cells
Method Development for Single-Cell Multi-omics
This study is looking at new ways to understand how changes in our genes and their regulation work together in individual cells, which could help us better predict how genes turn on and off in different tissues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10929321 on NIH RePORTER |
What this research studies
This research focuses on improving techniques to analyze various genetic and epigenetic modifications within individual cells. By utilizing advanced multi-omics technologies, the project aims to capture multiple measurements simultaneously, which is crucial for understanding how these factors influence gene regulation. The goal is to enhance our ability to study the complex interactions between different epigenetic marks and gene expression in diverse tissues. This could lead to more accurate predictive models for gene activation and repression.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions influenced by genetic and epigenetic factors, such as cancer or genetic disorders.
Not a fit: Patients with conditions that are not primarily driven by genetic or epigenetic changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding gene regulation, potentially improving treatments for various diseases.
How similar studies have performed: Other research has shown promise in using multi-omics approaches at the single-cell level, indicating potential for success in this area.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Liu, Yaping — Northwestern University at Chicago
- Study coordinator: Liu, Yaping
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.