Developing methods to analyze genetic data across different ages and tissues
Integrative Analysis Methods for the dGTEx Initiative
['FUNDING_U01'] · UNIVERSITY OF CHICAGO · NIH-10990871
This study is looking at how our genes change as we grow and how these changes can affect our health, using smart computer tools to help find important genes in both kids and adults.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10990871 on ClinicalTrials.gov |
What this research studies
This research focuses on creating innovative methods and tools to analyze genetic data from the Developmental Genotype-Tissue Expression (dGTEx) initiative and related studies. It aims to map genetic variations that affect gene expression across various developmental stages and tissue types. By employing advanced machine learning techniques, the research will identify risk genes and their causal effects in both children and adults. This integrative approach will enhance our understanding of how genetic factors influence health throughout different life stages.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals of all ages, particularly those with a family history of genetic disorders or developmental conditions.
Not a fit: Patients with no genetic predisposition to the conditions being studied may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved identification of genetic risk factors for diseases, ultimately enhancing prevention and treatment strategies for patients.
How similar studies have performed: Previous research using similar integrative analysis methods has shown promise in identifying genetic risk factors, indicating that this approach has the potential for success.
Where this research is happening
CHICAGO, UNITED STATES
- UNIVERSITY OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHEN, LIN — UNIVERSITY OF CHICAGO
- Study coordinator: CHEN, LIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.