Developing methods for manufacturing a new drug.
Official title: SLAUGENHAUPT-MGH DMFP FOR BPN36964 (PTC680)
Funded at Midwest Research Institute · NIH-10949228 · Data updated 2026-11-12
This study is working on developing a new drug called BPN36964 (PTC680) to help patients who need better treatment options, making sure it's safe and effective through careful testing.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Midwest Research Institute NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | September 19, 2023 |
| Project end | September 18, 2029 |
| Funding year | 2023 |
| Award (this year) | $1,030,591 |
| NIH project number | 271201500006I-0-759502300001-1 |
| Project ID | NIH-10949228 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation would be those who are affected by conditions that may be treated by the new drug being developed.
✕Less likely to help
Patients who do not have conditions that the new drug targets may not receive any benefit from this research.
What this research studies
This research focuses on creating and validating the analytical methods necessary for the production of a new drug, BPN36964 (PTC680). The approach involves ensuring that the manufacturing process meets safety and quality standards through rigorous testing and qualification of the methods used. Patients may benefit from this research as it aims to support the development of a new treatment option that could address unmet medical needs. The research will involve collaboration with various stakeholders to ensure that the drug is produced effectively and safely.
Why it matters
Potential benefit: If successful, this research could lead to the availability of a new treatment option for patients.
How similar studies have gone: While the specific drug and methods are novel, similar approaches in drug development have shown success in bringing new treatments to market.
Where this research is happening
-
Midwest Research Institute
Kansas City, United States Active
Researchers
- Principal investigator: Penny, Brian — Midwest Research Institute
- Study coordinator: Penny, Brian
Related research
Other NIH-funded projects on the same topics.
-
BRIDGE Center: A shared biomanufacturing hub to move biologics and cell therapies toward clinic
A new shared facility will help speed up the development and early clinical testing of vaccines, biologics, and cell-based therapies.
-
Developing a new treatment for tuberculosis called Telacebec.
This study is testing a new medication called Telacebec (Q203) to see if it can help people with tuberculosis by making treatment safer and more effective, which could lead to shorter recovery times and better health outcomes.
-
Creating a new type of DNA vaccine for better immune responses
This study is testing a new type of vaccine made from DNA that could help boost your immune system against different diseases, and it's designed to be safe and effective for people like you.
-
Developing a live biotherapeutic to improve vaginal health
This study is testing a new treatment made from good bacteria to help women with bacterial vaginosis and improve their vaginal health, which may also lower the risk of cervical issues.
-
Understanding and improving pain management.
This study is all about finding quicker and better ways to understand and manage pain, so that people dealing with different pain conditions can get more effective treatments and feel better.
-
A centralized resource for cancer prevention agents and support services
This study is creating a central place to store and manage cancer-fighting substances to help researchers find better ways to prevent cancer, making it easier for them to conduct their important work.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.