Developing long-lasting and patient-controlled local anesthesia for pain management
Prolonged duration and triggered local anesthesia
['FUNDING_OTHER'] · BOSTON CHILDREN'S HOSPITAL · NIH-11127444
This study is exploring new ways to deliver long-lasting pain relief for people dealing with pain from surgeries or ongoing conditions, so you can have more control over your comfort without relying heavily on opioids.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11127444 on ClinicalTrials.gov |
What this research studies
This research focuses on creating innovative injectable drug delivery systems that provide prolonged local anesthesia for patients experiencing pain, whether from surgical procedures or chronic conditions. The approach involves using sustained release technology to allow anesthesia to last from hours to weeks, reducing the need for opioids and their associated risks. Additionally, the study aims to develop systems that enable patients to control when and how much anesthesia they receive, using external energy sources like near-infrared light and ultrasound. This patient-centered method could significantly improve pain management and enhance the quality of care.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals undergoing surgical procedures or those suffering from chronic pain conditions.
Not a fit: Patients who do not experience pain or have contraindications to local anesthesia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective pain management options that minimize opioid use.
How similar studies have performed: Previous research has shown promise in developing sustained release drug delivery systems, indicating potential for success in this novel approach.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOHANE, DANIEL S — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: KOHANE, DANIEL S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.