Developing immunotherapy strategies for HIV-1 remission and eradication
I4C 2.0: Immunotherapy for Cure
['FUNDING_OTHER'] · BETH ISRAEL DEACONESS MEDICAL CENTER · NIH-11078704
This study is looking for new ways to help people with HIV-1 by finding out how the virus hides in the body and testing new treatments that could help keep the virus away for a long time or even get rid of it completely.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BETH ISRAEL DEACONESS MEDICAL CENTER (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11078704 on ClinicalTrials.gov |
What this research studies
This research aims to enhance our understanding of the viral reservoir in HIV-1 and to create immunologic strategies that could lead to long-term remission or complete eradication of the virus. It involves a collaborative effort among academia, industry, government, and community partners to explore various immunologic approaches, including therapeutic vaccines and engineered T and B cells. The research will focus on identifying the mechanisms behind viral persistence and testing innovative immune engineering strategies to improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV-1 who are seeking options for long-term remission or eradication of the virus.
Not a fit: Patients who are not living with HIV-1 or those who are not interested in experimental immunotherapy approaches may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that allow HIV-1 patients to maintain viral control without the need for ongoing antiretroviral therapy.
How similar studies have performed: Previous research has shown promise in using immunotherapy approaches for HIV-1, indicating that this multifaceted strategy could build on existing knowledge and successes.
Where this research is happening
BOSTON, UNITED STATES
- BETH ISRAEL DEACONESS MEDICAL CENTER — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAROUCH, DAN H. — BETH ISRAEL DEACONESS MEDICAL CENTER
- Study coordinator: BAROUCH, DAN H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.