Developing imaging probes for Alzheimer's disease
Official title: BET-BD1 Selective Neuroimaging probes for Alzheimer's disease research
Funded at Massachusetts General Hospital · NIH-10628245 · Data updated 2026-11-12
This study is looking to create new imaging tools that can help see a specific protein in the brains of people with Alzheimer's disease, which could lead to better ways to diagnose and treat the condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $2,442,345 |
| NIH project number | 1RF1AG081195-01 |
| Project ID | NIH-10628245 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those at risk of developing it.
✕Less likely to help
Patients with other forms of dementia unrelated to Alzheimer's may not benefit from this research.
What this research studies
This research focuses on creating new imaging probes that target a specific protein domain related to Alzheimer's disease. By using advanced techniques, the team aims to develop PET radiotracers that can visualize the BET-BD1 protein in the brain, which is crucial for understanding the disease's progression and the effects of potential treatments. The study will involve comparing these imaging techniques in healthy individuals and those with Alzheimer's to assess how well they work. This innovative approach could lead to better diagnostic tools and therapies for Alzheimer's patients.
Why it matters
Potential benefit: If successful, this research could provide new diagnostic tools and treatment options for patients with Alzheimer's disease.
How similar studies have gone: Previous research has shown promise in using imaging techniques for other neurodegenerative diseases, suggesting potential success for this novel approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Wang, Changning — Massachusetts General Hospital
- Study coordinator: Wang, Changning
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.