Developing imaging biomarkers for frontotemporal dementia
Super-Resolved Multimodal Imaging Biomarkers for Frontotemporal Dementia
['FUNDING_R21'] · UNIVERSITY OF MASSACHUSETTS AMHERST · NIH-11115762
This study is looking at new ways to use brain scans to help doctors better diagnose frontotemporal dementia and similar conditions, especially in younger people, by spotting specific changes in a part of the brain called the thalamus.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MASSACHUSETTS AMHERST (nih funded) |
| Locations | 1 site (HADLEY, UNITED STATES) |
| Trial ID | NIH-11115762 on ClinicalTrials.gov |
What this research studies
This research focuses on creating new imaging biomarkers to help diagnose and study frontotemporal dementia (FTD) and other related dementias. By using advanced imaging techniques, the team aims to identify specific changes in the thalamic nuclei of the brain that are associated with FTD. The study will analyze existing imaging data to validate these biomarkers, which could lead to earlier and more accurate diagnoses for patients. The research emphasizes the need for tools that can differentiate between various types of dementia, particularly in younger adults.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults under 65 years of age who are experiencing symptoms of frontotemporal dementia or have a genetic predisposition to the condition.
Not a fit: Patients with dementia types other than frontotemporal dementia, particularly those over 65 years of age, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools for frontotemporal dementia, allowing for earlier intervention and better management of the condition.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to identify biomarkers for Alzheimer's disease, suggesting that this approach may also be effective for frontotemporal dementia.
Where this research is happening
HADLEY, UNITED STATES
- UNIVERSITY OF MASSACHUSETTS AMHERST — HADLEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DUTTA, JOYITA — UNIVERSITY OF MASSACHUSETTS AMHERST
- Study coordinator: DUTTA, JOYITA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia