Developing human antibodies to fight COVID-19

Human antibody-based countermeasures against the Wuhan Coronavirus SARS-CoV-2

NIH-funded research Washington University · NIH-10902121

This study is looking at how certain antibodies from people who have recovered from COVID-19 can help fight the virus, with the goal of creating new treatments to keep patients from getting very sick.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10902121 on NIH RePORTER

What this research studies

This research focuses on creating and testing human monoclonal antibodies that can neutralize the SARS-CoV-2 virus, which causes COVID-19. The team will collect antibodies from individuals who have recovered from COVID-19 and analyze their effectiveness against the virus. By understanding how these antibodies bind to the virus, the researchers aim to develop treatments that could be used to prevent severe illness in patients. The project involves collaboration among experts to ensure rapid progress in developing these therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who are at high risk for severe COVID-19, such as the elderly or those with compromised immune systems.

Not a fit: Patients who are not at risk for severe COVID-19 or those who have already been vaccinated may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective antibody treatments that reduce the severity of COVID-19 and save lives.

How similar studies have performed: Other research has successfully developed antibody therapies for viral infections, indicating that this approach has potential for success.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Animal Disease Models
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.