Developing hormone-free gels to treat vaginal atrophy in post-menopausal women
Official title: Hormone-Free Prebiotic Muco-Adhesive Gels To Treat Vaginal Atrophy in Post-Menopausal Women
Funded at Moremme-Javore LLC · NIH-11247189 · Data updated 2026-11-12
This study is testing a new gel that can help relieve dryness and irritation for post-menopausal women dealing with vaginal atrophy, and it does so without using hormones, making it a safer option for those worried about side effects.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Moremme-Javore LLC NIH-funded |
| Lab location | 1 site (Hoover, United States) |
| Project start | August 15, 2024 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $67,079 |
| NIH project number | 6R43AG084468-02 |
| Project ID | NIH-11247189 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are post-menopausal women experiencing symptoms of vaginal atrophy.
✕Less likely to help
Patients who are not post-menopausal or those who do not experience symptoms of vaginal atrophy may not benefit from this research.
What this research studies
This research focuses on creating a new type of gel that can help treat vaginal atrophy, a common condition affecting many post-menopausal women. The gel is designed to be muco-adhesive, meaning it will stick to the vaginal walls and provide longer-lasting relief from symptoms like dryness and irritation without using hormones. By avoiding hormonal treatments, this approach aims to reduce concerns about side effects associated with estrogen therapies. The research will involve testing the effectiveness and safety of these gels in women experiencing vaginal atrophy.
Why it matters
Potential benefit: If successful, this research could provide a safe and effective non-hormonal treatment option for vaginal atrophy, improving the quality of life for many post-menopausal women.
How similar studies have gone: While hormone-free treatments for vaginal atrophy are being explored, this specific approach using muco-adhesive gels is relatively novel and has not been widely tested.
Where this research is happening
-
Moremme-Javore LLC
Hoover, United States Active
Researchers
- Principal investigator: Akande-Dokun, Janet — Moremme-Javore LLC
- Study coordinator: Akande-Dokun, Janet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.