Developing hormone-free gels to treat vaginal atrophy in post-menopausal women

Hormone-Free Prebiotic Muco-Adhesive Gels To Treat Vaginal Atrophy in Post-Menopausal Women

NIH-funded research Moremme-Javore LLC · NIH-11247189

This study is testing a new gel that can help relieve dryness and irritation for post-menopausal women dealing with vaginal atrophy, and it does so without using hormones, making it a safer option for those worried about side effects.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionMoremme-Javore LLC NIH-funded
Lab location1 site (Hoover, United States)
Project IDNIH-11247189 on NIH RePORTER

What this research studies

This research focuses on creating a new type of gel that can help treat vaginal atrophy, a common condition affecting many post-menopausal women. The gel is designed to be muco-adhesive, meaning it will stick to the vaginal walls and provide longer-lasting relief from symptoms like dryness and irritation without using hormones. By avoiding hormonal treatments, this approach aims to reduce concerns about side effects associated with estrogen therapies. The research will involve testing the effectiveness and safety of these gels in women experiencing vaginal atrophy.

Who could benefit from this research

Good fit: Ideal candidates for this research are post-menopausal women experiencing symptoms of vaginal atrophy.

Not a fit: Patients who are not post-menopausal or those who do not experience symptoms of vaginal atrophy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a safe and effective non-hormonal treatment option for vaginal atrophy, improving the quality of life for many post-menopausal women.

How similar studies have performed: While hormone-free treatments for vaginal atrophy are being explored, this specific approach using muco-adhesive gels is relatively novel and has not been widely tested.

Where this research is happening

Hoover, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.