Developing genetic tools using chicken embryonic stem cells
Chicken embryonic stem cells
['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11064860
This study is all about finding new ways to change the genes of chickens and other birds to help with research and protect endangered species, making it easier to create birds with specific traits.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-11064860 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a platform for genetically modifying chickens and other avian species by deriving germline competent embryonic stem cells (ESCs) from chicken embryos. The project aims to establish methods for generating chicken germline chimeras and primordial germ cells, which will facilitate the production of genetically modified chickens. Additionally, the research will explore the generation of induced pluripotent stem cells from chicken embryonic fibroblasts. This work is significant for advancing developmental biology and conservation efforts for endangered bird species.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include researchers and conservationists working with avian species, particularly those focused on genetic modification and conservation.
Not a fit: Patients who are not involved in avian research or do not work with chickens or other birds may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide essential genetic tools for producing transgenic chickens, enhancing agricultural practices and conservation efforts.
How similar studies have performed: Other research has shown success in using embryonic stem cells for genetic modification in various species, indicating a promising avenue for this novel approach in avian species.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YING, QILONG — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: YING, QILONG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.