Developing genetic tools using chicken embryonic stem cells
Official title: Chicken embryonic stem cells
Funded at University of Southern California · NIH-11064860 · Data updated 2026-11-12
This study is all about finding new ways to change the genes of chickens and other birds to help with research and protect endangered species, making it easier to create birds with specific traits.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | July 19, 2023 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $332,000 |
| NIH project number | 5R01GM151373-03 |
| Project ID | NIH-11064860 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include researchers and conservationists working with avian species, particularly those focused on genetic modification and conservation.
✕Less likely to help
Patients who are not involved in avian research or do not work with chickens or other birds may not receive any benefit from this research.
What this research studies
This research focuses on creating a platform for genetically modifying chickens and other avian species by deriving germline competent embryonic stem cells (ESCs) from chicken embryos. The project aims to establish methods for generating chicken germline chimeras and primordial germ cells, which will facilitate the production of genetically modified chickens. Additionally, the research will explore the generation of induced pluripotent stem cells from chicken embryonic fibroblasts. This work is significant for advancing developmental biology and conservation efforts for endangered bird species.
Why it matters
Potential benefit: If successful, this research could provide essential genetic tools for producing transgenic chickens, enhancing agricultural practices and conservation efforts.
How similar studies have gone: Other research has shown success in using embryonic stem cells for genetic modification in various species, indicating a promising avenue for this novel approach in avian species.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Ying, Qilong — University of Southern California
- Study coordinator: Ying, Qilong
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.