Developing films that prevent blood clots for medical devices
Rechargeable Anti-thrombogenic Films for Blood Contacting Applications
This study is working on new special films for heart devices that help prevent blood clots, which could make life easier and safer for patients with these devices.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10997328 on NIH RePORTER |
What this research studies
This research focuses on creating innovative films that can be applied to cardiovascular devices to prevent blood clots. By utilizing advanced techniques, the team aims to develop synthetic heparins that resist degradation and can be recharged to maintain their anti-thrombotic properties. The approach involves both computational and experimental methods to ensure the safety and effectiveness of these films. Patients with implanted cardiovascular devices may benefit from improved device performance and reduced complications related to blood clotting.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have or will undergo implantation of cardiovascular devices.
Not a fit: Patients without cardiovascular devices or those not at risk for thrombus formation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance the safety and longevity of cardiovascular devices for patients.
How similar studies have performed: Previous research has shown promise in using similar approaches to enhance the performance of blood-contacting materials, indicating potential for success in this area.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Chaikof, Elliot — Beth Israel Deaconess Medical Center
- Study coordinator: Chaikof, Elliot
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.