Developing films that prevent blood clots for medical devices
Official title: Rechargeable Anti-thrombogenic Films for Blood Contacting Applications
Funded at Beth Israel Deaconess Medical Center · NIH-10997328 · Data updated 2026-11-12
This study is working on new special films for heart devices that help prevent blood clots, which could make life easier and safer for patients with these devices.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $652,429 |
| NIH project number | 5R01HL171101-02 |
| Project ID | NIH-10997328 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have or will undergo implantation of cardiovascular devices.
✕Less likely to help
Patients without cardiovascular devices or those not at risk for thrombus formation may not benefit from this research.
What this research studies
This research focuses on creating innovative films that can be applied to cardiovascular devices to prevent blood clots. By utilizing advanced techniques, the team aims to develop synthetic heparins that resist degradation and can be recharged to maintain their anti-thrombotic properties. The approach involves both computational and experimental methods to ensure the safety and effectiveness of these films. Patients with implanted cardiovascular devices may benefit from improved device performance and reduced complications related to blood clotting.
Why it matters
Potential benefit: If successful, this research could significantly enhance the safety and longevity of cardiovascular devices for patients.
How similar studies have gone: Previous research has shown promise in using similar approaches to enhance the performance of blood-contacting materials, indicating potential for success in this area.
Where this research is happening
-
Beth Israel Deaconess Medical Center
Boston, United States Active
Researchers
- Principal investigator: Chaikof, Elliot — Beth Israel Deaconess Medical Center
- Study coordinator: Chaikof, Elliot
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.