Developing fast imaging techniques to analyze brain tissue for Alzheimer's disease
Official title: High-speed hyperspectral imaging for highly multiplexed immunofluorescence imaging
Funded at Numentus Technologies INC. · NIH-10699518 · Data updated 2026-11-12
This study is looking at new ways to take pictures of brain tissue to help doctors better understand and diagnose Alzheimer's disease, so patients can get more accurate and effective treatments.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Numentus Technologies INC. NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $300,691 |
| NIH project number | 1R43MH135772-01 |
| Project ID | NIH-10699518 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias.
✕Less likely to help
Patients with other types of dementia not related to Alzheimer's disease may not benefit from this research.
What this research studies
This research focuses on improving imaging techniques to analyze brain tissue samples, specifically for conditions like Alzheimer's disease. By utilizing advanced hyperspectral imaging, the project aims to enable the detection of multiple molecular targets in a single tissue sample quickly and cost-effectively. This approach seeks to enhance the capabilities of traditional immunohistochemistry methods, which are currently limited in their ability to analyze complex networks of proteins. Patients may benefit from more accurate and efficient diagnostic tools that can lead to better understanding and treatment of Alzheimer's disease.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnostic methods for Alzheimer's disease, improving patient care.
How similar studies have gone: Other research has shown promise in using advanced imaging techniques for similar applications, indicating potential for success in this area.
Where this research is happening
-
Numentus Technologies INC.
Menlo Park, United States Active
Researchers
- Principal investigator: Faris, Gregory W — Numentus Technologies INC.
- Study coordinator: Faris, Gregory W
Related research
Other NIH-funded projects on the same topics.
-
Multiplexed blood biomarkers for Alzheimer’s disease subtypes
A new test uses many extracellular vesicle signals from blood to help identify different Alzheimer’s subtypes and guide better diagnosis.
-
Analyzing tiny particles from cells for better diagnostics and therapies
This study is exploring a new way to look at tiny particles released by cells that can provide important clues about cancer and infections, with the goal of helping doctors find better ways to diagnose and treat patients.
-
Developing a faster and more versatile PCR method for DNA and RNA testing
This study is working on a new, faster, and more portable machine to help doctors quickly test for infections like the flu by improving how we copy DNA and RNA, so patients can get their results in just minutes instead of hours.
-
Exploring bacterial outer membrane vesicles for diagnostics and therapies
This study is exploring how tiny bubbles released by bacteria could help us find and treat infections better by looking closely at what’s inside them, making it easier to identify specific bacterial infections.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.