Developing eco-friendly methods to create nitrogen-containing compounds

Ni-catalyzed sustainable and scalable approaches to nitrogenated compounds

NIH-funded research University of California Riverside · NIH-11117138

This study is exploring a safer and more affordable way to make important chemicals used in medicines and other products by using special nickel-based materials that work at normal temperatures, instead of needing harmful substances or high heat.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Riverside NIH-funded
Lab location1 site (Riverside, United States)
Project IDNIH-11117138 on NIH RePORTER

What this research studies

This research focuses on creating sustainable methods using nickel-based catalysts to synthesize important nitrogen-containing molecules like amines, amides, and nitriles. The approach aims to overcome challenges in current methods, such as the need for toxic reagents and high temperatures, by enabling reactions at ambient conditions. This could lead to safer and more cost-effective production processes for these compounds, which are vital in pharmaceuticals and other industries.

Who could benefit from this research

Good fit: Patients who may benefit from this research include those requiring medications that contain nitrogen-based compounds, such as certain antibiotics and antidepressants.

Not a fit: Patients who do not require nitrogen-containing medications or who are not affected by the availability of these compounds may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more efficient production of essential drugs and materials.

How similar studies have performed: Previous research has shown promise in using nickel catalysts for similar chemical processes, indicating potential for success in this novel approach.

Where this research is happening

Riverside, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.