Developing eco-friendly methods to create nitrogen-containing compounds
Official title: Ni-catalyzed sustainable and scalable approaches to nitrogenated compounds
Funded at University of California Riverside · NIH-11117138 · Data updated 2026-11-12
This study is exploring a safer and more affordable way to make important chemicals used in medicines and other products by using special nickel-based materials that work at normal temperatures, instead of needing harmful substances or high heat.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project start | July 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $372,165 |
| NIH project number | 5R35GM154874-02 |
| Project ID | NIH-11117138 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients who may benefit from this research include those requiring medications that contain nitrogen-based compounds, such as certain antibiotics and antidepressants.
✕Less likely to help
Patients who do not require nitrogen-containing medications or who are not affected by the availability of these compounds may not benefit from this research.
What this research studies
This research focuses on creating sustainable methods using nickel-based catalysts to synthesize important nitrogen-containing molecules like amines, amides, and nitriles. The approach aims to overcome challenges in current methods, such as the need for toxic reagents and high temperatures, by enabling reactions at ambient conditions. This could lead to safer and more cost-effective production processes for these compounds, which are vital in pharmaceuticals and other industries.
Why it matters
Potential benefit: If successful, this research could lead to safer and more efficient production of essential drugs and materials.
How similar studies have gone: Previous research has shown promise in using nickel catalysts for similar chemical processes, indicating potential for success in this novel approach.
Where this research is happening
-
University of California Riverside
Riverside, United States Active
Researchers
- Principal investigator: Bahamonde, Ana — University of California Riverside
- Study coordinator: Bahamonde, Ana
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.