Developing early trials to prevent obesity-related cancers

Early Phase Clinical Cancer Prevention Consortium

NIH-funded research University of Michigan at Ann Arbor · NIH-10886009

This study is looking for ways to prevent certain cancers linked to obesity by focusing on special cancer cells, and it invites patients to join in testing new methods that could help lower the risk of cancers like breast, bladder, and colon cancer.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10886009 on NIH RePORTER

What this research studies

This research focuses on early clinical trials aimed at preventing cancers associated with obesity by targeting stem-like cancer cells. It investigates how chronic inflammatory stress, such as that caused by obesity and exposure to certain chemicals, can lead to increased cancer cell growth. The consortium plans to conduct multiple trials each year, testing various preventive agents that may help reduce the risk of cancers like breast, bladder, and colon cancer. Patients may have the opportunity to participate in these trials and contribute to the development of new cancer prevention strategies.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals at high risk for obesity-related cancers, particularly those with obesity or metabolic syndrome.

Not a fit: Patients who do not have obesity or related risk factors for the cancers being studied may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new preventive treatments for obesity-related cancers, potentially reducing cancer incidence in at-risk populations.

How similar studies have performed: Other research has shown promise in targeting stem-like cancer cells for prevention, suggesting that this approach may be effective.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Bladder CancerBreast Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.