Developing coatings that prevent bacterial growth using liquid-infused surfaces
Slippery Liquid-Infused Polymer Coatings that Release Hydrophilic Antimicrobial Agents
['FUNDING_R21'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-11046613
This study is exploring new surfaces that can help keep hospitals cleaner by releasing special agents to fight off harmful bacteria, which could lead to safer medical devices and a lower risk of infections for patients.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11046613 on ClinicalTrials.gov |
What this research studies
This research focuses on creating innovative surfaces that can release antibiotics and anti-virulence agents to combat bacterial fouling in healthcare settings. The project aims to design new types of liquid-infused porous surfaces, known as 'SLIPS', which can effectively reduce bacterial load and prevent harmful bacterial behaviors. By utilizing these advanced coatings, the research seeks to address persistent challenges in maintaining sterile environments in clinical settings. Patients may benefit from improved medical devices and surfaces that minimize the risk of infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing procedures involving medical devices or implants that are at risk of bacterial infection.
Not a fit: Patients who are not undergoing any medical procedures or do not have devices that could be affected by bacterial fouling may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to significant reductions in healthcare-associated infections by improving the surfaces of medical devices and equipment.
How similar studies have performed: Previous research has shown promise in using liquid-infused surfaces for antifouling applications, indicating that this approach may be effective.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LYNN, DAVID M — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: LYNN, DAVID M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.