Developing brain-computer interfaces for communication in patients with severe impairments

Intuitive, complete neural control of tablet computers for communication

['FUNDING_U01'] · BROWN UNIVERSITY · NIH-10861879

This study is exploring new technology that helps people with severe speech and movement challenges, like those with ALS or brainstem strokes, to communicate just by using their brain activity, making it easier for them to connect without needing to move their bodies.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorBROWN UNIVERSITY (nih funded)
Locations1 site (PROVIDENCE, UNITED STATES)
Trial IDNIH-10861879 on ClinicalTrials.gov

What this research studies

This research focuses on creating advanced brain-computer interfaces (BCIs) that allow individuals with severe speech and motor impairments, such as those caused by amyotrophic lateral sclerosis (ALS) or brainstem strokes, to communicate without relying on physical movements. The approach involves decoding brain activity to control communication applications directly, providing a more intuitive and efficient means of interaction. By eliminating the need for residual motor function, this technology aims to enhance communication for patients who may otherwise be unable to use traditional augmentative and alternative communication (AAC) devices.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with severe speech and motor impairments due to conditions like ALS or brainstem strokes.

Not a fit: Patients with intact speech and motor functions are unlikely to benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve communication abilities for patients with severe motor impairments, enhancing their quality of life.

How similar studies have performed: Previous research has shown promising results with brain-computer interfaces, indicating potential for success in this novel approach.

Where this research is happening

PROVIDENCE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Amyotrophic Lateral Sclerosis Motor Neuron Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.