Developing blood tests to identify lung cancer risk early

Clinical Validation Center for Lung Cancer Early Detection

['FUNDING_U01'] · UNIVERSITY OF TX MD ANDERSON CAN CTR · NIH-10916386

This study is looking to develop a simple blood test that can help figure out who is at risk for lung cancer, so that people can get checked earlier and possibly treated sooner, even if they don’t fit the usual guidelines for screening.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TX MD ANDERSON CAN CTR (nih funded)
Locations1 site (HOUSTON, UNITED STATES)
Trial IDNIH-10916386 on ClinicalTrials.gov

What this research studies

This research aims to create a blood-based biomarker panel that helps assess individual risk for lung cancer, potentially leading to earlier detection and treatment. By analyzing a combination of protein markers, the study seeks to identify patients who may benefit from CT screening, even if they do not meet current eligibility criteria. Additionally, the research will explore how artificial intelligence can enhance the interpretation of CT images and personalize screening schedules based on individual risk factors. Patients will be involved in a decision-sharing process to better understand their risk and screening options.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at high risk for lung cancer who may not currently qualify for routine screening based on existing guidelines.

Not a fit: Patients with low risk for lung cancer or those who are already diagnosed with lung cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection of lung cancer, improving treatment outcomes and survival rates for patients.

How similar studies have performed: Previous research has shown promise in using biomarker panels for cancer detection, indicating that this approach may lead to significant advancements in early diagnosis.

Where this research is happening

HOUSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.