Developing blood tests to identify cancer biomarkers
Official title: Biomarker Development Laboratory
Funded at New York University School of Medicine · NIH-11081761 · Data updated 2026-11-12
This study is looking at blood samples to find tiny signs of germs that might help us spot lung cancer earlier, especially a type called non-small cell lung cancer, and we invite patients to share their blood to help us discover new ways to diagnose and understand this disease better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 4, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $339,874 |
| NIH project number | 5U2CCA271890-03 |
| Project ID | NIH-11081761 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for lung cancer or those diagnosed with non-small cell lung cancer.
✕Less likely to help
Patients with cancers other than lung cancer or those not at risk for lung cancer may not benefit from this research.
What this research studies
This research focuses on using advanced techniques to analyze blood samples for microbial signatures that may indicate the presence of lung cancer. By employing shotgun metagenomics, the study aims to identify specific microbial DNA patterns in the bloodstream that correlate with different types of cancer, particularly non-small cell lung cancer (NSCLC). The research will also explore the relationship between these microbial signatures and host genomic features, as well as the metabolic environment, to develop novel biomarkers for early cancer diagnosis and prognosis. Patients may contribute blood samples to help identify these potential biomarkers.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and earlier detection of lung cancer through blood tests.
How similar studies have gone: Previous research has shown promise in using microbial signatures for cancer diagnosis, indicating that this approach could be a valuable advancement in the field.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Segal, Leopoldo Nicolas — New York University School of Medicine
- Study coordinator: Segal, Leopoldo Nicolas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.