Developing blood tests to assess the risk of breast and ovarian cancer.
Official title: Blood-Based Biomarkers for Personalized Risk Assessment of Breast and Ovarian Cancer
Funded at University of Tx Md Anderson Can Ctr · NIH-10931706 · Data updated 2026-11-12
This study is looking to develop blood tests that can help figure out your personal risk for breast and ovarian cancer by checking for certain proteins and antibodies in your blood, so you can get better recommendations for screenings and early detection.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $638,683 |
| NIH project number | 5U01CA282216-02 |
| Project ID | NIH-10931706 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who are at risk for breast or ovarian cancer, particularly those with a family history or other risk factors.
✕Less likely to help
Patients who have already been diagnosed with breast or ovarian cancer may not benefit from this research.
What this research studies
This research aims to create blood-based biomarker tests that help personalize the assessment of breast and ovarian cancer risk for individuals. By analyzing circulating proteins and autoantibodies in the blood, the study seeks to identify specific markers that indicate a person's likelihood of having these cancers. The results will be integrated with existing risk models to provide tailored recommendations for screening and surveillance, enhancing early detection efforts. The research utilizes data from a large cohort of participants to validate the effectiveness of these biomarkers.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and personalized cancer risk assessments, improving early detection and prevention strategies for breast and ovarian cancer.
How similar studies have gone: Previous research has shown promise in using blood-based biomarkers for cancer detection, indicating that this approach could be effective.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Fahrmann, Johannes F — University of Tx Md Anderson Can Ctr
- Study coordinator: Fahrmann, Johannes F
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.