Developing blood tests for early cancer detection using DNA markers

Administrative Core

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-10902049

This study is working on developing blood tests that can help find cancer early by looking at changes in DNA, and it's being done by a team of experts to make sure the tests are reliable and useful for patients like you.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-10902049 on NIH RePORTER

What this research studies

This research focuses on creating and validating blood-based biomarkers that can help detect cancer early. A team of experts from three leading cancer centers will collaborate to develop these tests, which involve analyzing DNA methylation patterns in blood samples. The project aims to streamline the process from initial discovery to clinical application, ensuring that the tests are reliable and effective for patient use. By coordinating efforts across multiple institutions, the research seeks to enhance the accuracy and efficiency of cancer detection methods.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at high risk for cancer or those undergoing routine cancer screenings.

Not a fit: Patients with cancers that are not detectable through blood-based biomarkers may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and earlier detection of cancers, improving treatment outcomes for patients.

How similar studies have performed: Previous research has shown promise in using DNA methylation biomarkers for cancer detection, indicating a potential for success in this approach.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions CancersComprehensive Cancer Center
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.