Developing biomarkers to improve lung nodule diagnosis
Biomarker Development Lab
['FUNDING_OTHER'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-10888983
This study is looking for better ways to tell if lung nodules found on CT scans are harmless or cancerous, so that patients with uncertain nodules can get the right care without unnecessary procedures.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY MEDICAL CAMPUS (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10888983 on ClinicalTrials.gov |
What this research studies
This research focuses on creating and validating new biomarkers to help distinguish between benign and malignant pulmonary nodules detected through CT scans. By analyzing nasal gene expression, circulating tumor cells, and CT imaging, the project aims to improve the clinical management of patients with intermediate-risk nodules. The goal is to reduce unnecessary invasive procedures and ensure timely treatment for those with malignant nodules. Patients with indeterminate pulmonary nodules will benefit from more accurate risk stratification and management.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been found to have indeterminate pulmonary nodules through CT scans.
Not a fit: Patients with clearly benign or malignant nodules may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better management of lung nodules, reducing unnecessary procedures and improving patient outcomes.
How similar studies have performed: Previous research has shown promise in developing biomarkers for cancer detection, indicating potential success for this novel approach.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY MEDICAL CAMPUS — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DUBINETT, STEVEN M. — BOSTON UNIVERSITY MEDICAL CAMPUS
- Study coordinator: DUBINETT, STEVEN M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers